Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7] (E-AB-F1035A)
| Isotype | Armenian Hamster IgG |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD120b/TNFR2 |
| Synonyms | CD120b, TNF-R2, TNF-RII, TNFR-II, Tnfrsf1b, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, p75, p80 TNF-alpha receptor |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Research Areas | Immunology, Innate Immunity |
| Clone No. | TR75-54.7 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. |
| Cat.No. | Product Name | Clone No. |
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