Purified Anti-Mouse CD161/NK1.1 Antibody[PK136] (E-AB-F0987A)
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For research use only.
Conjugation: Unconjugated
APC Biotin Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Violet 450 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Mouse IgG2a, κ |
| Host | Mouse |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse NK1.1 protein |
| Abbre | NK1.1 |
| Synonyms | CD161 antigen-like family member C, CD161/NK1.1, CD161c, Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, Ly-55c, NKR-P1 40, NKR-P1.9, NKR-P1C |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology, Innate Immunity |
| Clone No. | PK136 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |
| Cat.No. | Product Name | Clone No. |
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