RAB27A Polyclonal Antibody

    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-15324

      Synonyms:GS2,GTP-binding protein Ram,HsT18676,MGC117246,Mutant Ras related protein Rab-27A,Rab-27,RAB-27A,RAB27,RAB27A,RAB27A member RAS oncogene family,RAM,Ras-related protein Rab-27A,Ras-related protein Rab27A,RB27A

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms GS2,GTP-binding protein Ram,HsT18676,MGC117246,Mutant Ras related protein Rab-27A,Rab-27,RAB-27A,RAB27,RAB27A,RAB27A member RAS oncogene family,RAM,Ras-related protein Rab-27A,Ras-related protein Rab27A,RB27A
      Swissprot P51159
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human RAB27A
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane. Melanosome. Late endosome. Lysosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localizes to endosomal exocytic vesicles.
      Tissue specificity Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta. Detected in melanocytes, and in most tumor cell lines examined. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

      Images

      Western Blot analysis of K562 cell using RAB27A Polyclonal Antibody at dilution of 1:400

      Immunohistochemistry of paraffin-embedded Human liver cancer using RAB27A Polyclonal Antibody at dilution of 1:30

      Citations

      1. Publication: Roberto C, Valeria R, Cristina N, et al. Gut-Derived Endotoxin Stimulates Factor Viii Secretion From Endothelial Cells. Implications For Hypercoagulability In Cirrhosis[J]. Journal of Hepatology, 2017.
        Sample Type: Cells, Cell lysis
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      MSDS for ELISA

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