RAC2 Polyclonal Antibody (E-AB-53322)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RAC2 |
| Abbre | RAC2 |
| Synonyms | EN 7, EN-7, EN7, GX, HSPC 022, HSPC022, RAC 2, RAC2, Rac2, Ras related C3 botulinum toxin substrate, Ras related C3 botulinum toxin substrate 2, Ras related C3 botulinum toxin substrate 2 (rho family, p21 Rac 2, p21 Rac2, p21-Rac2, p21Rac2, small GTP binding protein Rac2 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Membrane-associated when activated. |
| Concentration | 1.02 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome. |
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