RAMP3 Polyclonal Antibody

Uniprot : O60896
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14309

      Synonyms:Calcitonin receptor like receptor activity modifying protein 3,CRLR activity modifying protein 3,CRLR activity-modifying protein 3,OTTHUMP00000159549,OTTHUMP00000214279,OTTHUMP00000214280,Receptor (calcitonin) activity modifying protein 3,Receptor (G protein-coupled) activity modifying protein 3,Receptor activity modifying protein 3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Calcitonin receptor like receptor activity modifying protein 3,CRLR activity modifying protein 3,CRLR activity-modifying protein 3,OTTHUMP00000159549,OTTHUMP00000214279,OTTHUMP00000214280,Receptor (calcitonin) activity modifying protein 3,Receptor (G protein-coupled) activity modifying protein 3,Receptor activity modifying protein 3
      Swissprot O60896
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human RAMP3
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell Membrane; Single-pass type I membrane protein
      Tissue specificity Strongly expressed in lung, breast, immune system and fetal tissues.1 Publication
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

      Images

      Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using RAMP3 Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RAMP3 Polyclonal Antibody at dilution 1:40

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