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Recombinant Cynomolgus 5'-Nucleotidase/CD73/NT5E Protein (His Tag)

Cat:PKSQ050049
Manual MSDS

Price: $ 817

Price: $ 447

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: G7P3J1
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Product Details
Synonyms 5'-Nucleotidase;5'-NT;Ecto-5'-Nucleotidase;CD73;NT5E;NT5;NTE
Species Cynomolgus macaques
Expression Host HEK293 Cells
Sequence Trp27-Lys547
Accession G7P3J1
Calculated Molecular Weight 58.8 kDa
Observed Molecular Weight 58-80 kDa
Tag C-His
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 120mM NaCl, 4mM CaCl2, 20% Glycerol, pH 7.5.
Reconstitution Not Applicable
Background CD73, also known as Ecto-5'-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.