Click here to view cell apoptosis assay products
×

Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)

Uniprot : A0A7N9CAT7
  • Cat.No.:PKSQ050102

  • Expression host: E.coli

To Purchase PKSQ050102

Size:
  • 10μg
  • 50μg
Price: $130
Qty:

Description

Synonyms Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;TSLP
Species Cynomolgus macaques
Expression_host E.coli
Sequence Tyr29-Gln159(Glu37Gln)
Accession XP_005557555.1
Mol_Mass 16.2 kDa
AP_Mol_Mass 16 kDa
Tag C-His
Bio_Activity Loaded Anti-Human TSLP mAb-Fc on Protein A Biosensor, can bind Cynomolgus TSLP-His with an affinity constant of 0.07 nM as determined in BLI assay. 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 6% Trehalose, 2% Glycine, 50mM NaCl, 0.05% Tween 80, pH7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the
Reconstitution Please refer to the printed manual for detailed information.

Background

Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.

Citations

Reviews/Q&A

  • Show all
  • Reviews
  • Q&A
... Show All Show Less

People Also Bought

Apply for
*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?

*Captcha: