Synonyms	Anterior Gradient Protein 3 Homolog;AG-3;AG3;hAG-3;Breast Cancer Membrane Protein 11;AGR3;BCMP11
Species	Human
Expression_host	HEK293 Cells
Sequence	Ile22-Leu166
Accession	Q8TD06
Mol_Mass	18.0 kDa
AP_Mol_Mass	16 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Glycine-HCl, 10% Trehalose, 0.05% Tween80, pH3.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer info
Reconstitution	Please refer to the printed manual for detailed information.

Background

Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan (hAG-3 protein). AG-3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.

Citations

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