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Recombinant Human APN Protein (His Tag)

Cat:PKSR030495
Manual MSDS

Price: $ 768

Price: $ 253

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: P15144
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Product Details
Synonyms Aminopeptidase N;ANPEP;AP-M;APN;AP-N;CD13 antigen;CD13;CD13APN;PEPN;PEPNhAPN
Species Human
Expression Host HEK293 Cells
Sequence Lys69-Lys967
Accession P15144
Calculated Molecular Weight 103.5 kDa
Observed Molecular Weight 110-130 kDa
Tag C-His
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.
Reconstitution Not Applicable
Background ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.