Recombinant Human ASXL1 Protein (GST Tag)

    • Recombinant Human ASXL1 Protein (N-GST)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human ASXL1 Protein (N-GST)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human ASXL1 Protein (N-GST)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033781

      Synonyms:Putative Polycomb group protein ASXL1; Additional sex combs-like protein 1; ASXL1; KIAA0978;

      Size:
      • 10μg
      • 50μg
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      Price: $328

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      Overview

      Synonyms Putative Polycomb group protein ASXL1; Additional sex combs-like protein 1; ASXL1; KIAA0978;
      Species Human
      Expression_host E.coli
      Sequence Lys1477-Arg154
      Accession Q8IXJ9
      Mol_Mass 33.6 kDa
      AP_Mol_Mass 38 kDa
      Tag N-GST

      Properties

      Purity > 90% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.

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