Recombinant Human BCL2L1/Bcl-XL Protein (His Tag)

    • Recombinant Human BCL2L1 / Bcl-XL Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human BCL2L1 / Bcl-XL Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human BCL2L1 / Bcl-XL Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033757

      Synonyms:Bcl-2-Like Protein 1; Bcl2-L-1; Apoptosis Regulator Bcl-X; Bcl-X;bcl-xL;BCL-XL/S;bcl-xS;BCL2L;BCLX;BCLXL;BCLXS;PPP1R52

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $275

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      Overview

      Synonyms Bcl-2-Like Protein 1; Bcl2-L-1; Apoptosis Regulator Bcl-X; Bcl-X;bcl-xL;BCL-XL/S;bcl-xS;BCL2L;BCLX;BCLXL;BCLXS;PPP1R52
      Species Human
      Expression_host E.coli
      Sequence Met1-Arg212
      Accession Q07817
      Mol_Mass 24.85 kDa
      AP_Mol_Mass 29 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM HEPES, 50mM KCl, 20% Glycerol, pH 7.5.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.

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      MSDS for ELISA ISO 9001

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