Recombinant Human BCMA/TNFRSF17 Protein (mFc Tag)

    • Recombinant Human BCMA / TNFRSF17 / CD269 Protein (C-mFc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human BCMA / TNFRSF17 / CD269 Protein (C-mFc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human BCMA / TNFRSF17 / CD269 Protein (C-mFc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033485

      Synonyms:Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $144

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      Overview

      Synonyms Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma
      Species Human
      Expression_host Human Cells
      Sequence Met1-Ala54
      Accession Q02223
      Mol_Mass 32.5 kDa
      AP_Mol_Mass 35-42 kDa
      Tag C-mFc

      Properties

      Purity > 90% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane domain, and a 113 aa intracellular domain. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development,function and regulation.

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      MSDS for ELISA ISO 9001

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