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Recombinant Human Carbonic Anhydrase IX/CA9 (C-Avi-6His) Biotinylated

Uniprot : Q16790

Cat.No.:PKSH033862
Expression host: HEK293 Cells

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Description

Synonyms	CA9;CA-IX;Carbonic Anhydrase IX;Carbonate dehydratase IX;G250;MN;P54/58N;RCC;RCC-associated protein G250
Species	Human
Expression_host	HEK293 Cells
Sequence	Gln38-Asp414
Accession	Q16790
Mol_Mass	43.6 kDa
AP_Mol_Mass	60 kDa
Tag	C-Avi-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.

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