Synonyms	MGC138422;MGC138424
Species	Human
Expression_host	E.coli
Sequence	Ala2-Leu527
Accession	P04040
Mol_Mass	59.7 kDa
AP_Mol_Mass	60 kDa
Tag	None

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution	Not Applicable

Background

Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase is localized in the peroxisome. Catalase promotes growth of cells including T-cells; B-cells; myeloid leukemia cells; melanoma cells; mastocytoma cells; and normal and transformed fibroblast cells. Defects in CAT are the cause of acatalasemia which is characterized by absence of catalase activity in red cells and is associated with ulcerating oral lesions.

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