Synonyms	Coiled-coil domain-containing protein 134;
Species	Human
Expression_host	HEK293 Cells
Sequence	Thr 23-Leu229
Accession	Q9H6E4
Mol_Mass	25.3 kDa
AP_Mol_Mass	28-33 kDa
Tag	C-His
Bio_Activity	Not validated for activity

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Coiled-coil domain-containing protein 134(CCDC134), which is short for Coiled-coil domain-containing protein 134, belongs to the UPF0388 family. Human CCDC134 cDNA encodes a 229 amino acid (aa) precursor that contains a 22 aa signal peptide and a 207 aa with coiled-coil domain protein. Coiled-coil domain is a motif in which alpha-helix are coiled together. This protein is usually expressed in extracellular region. CCDC134 is also considered as a novel human MAPK-regulating protein that can inhibit the MAPK pathway.

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