Recombinant Human CCL8/MCP-2 Protein

    • Recombinant Human CCL8 / MCP-2 Protein-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human CCL8 / MCP-2 Protein-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human CCL8 / MCP-2 Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033731

      Synonyms:C-C Motif Chemokine 8; HC14; Monocyte Chemoattractant Protein 2; Monocyte Chemotactic Protein 2; MCP-2; Small-Inducible Cytokine A8; CCL8; MCP2; SCYA10; SCYA8;HC14

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $178

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms C-C Motif Chemokine 8; HC14; Monocyte Chemoattractant Protein 2; Monocyte Chemotactic Protein 2; MCP-2; Small-Inducible Cytokine A8; CCL8; MCP2; SCYA10; SCYA8;HC14
      Species Human
      Expression_host E.coli
      Sequence Gln24-Pro99
      Accession P80075
      Mol_Mass 8.9 kDa
      AP_Mol_Mass 12 kDa

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.

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