Recombinant Human CD155/PVR/NECL5 Protein (His Tag)(Active)

    • Recombinant Human CD155 / PVR / NECL5 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human CD155 / PVR / NECL5 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human CD155 / PVR / NECL5 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033563

      Synonyms:Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $275

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      Overview

      Synonyms Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS
      Species Human
      Expression_host Human Cells
      Sequence Trp21-Asn343(Ile340Met)
      Accession P15151
      Application Functional ELISA
      Mol_Mass 36.13 kDa
      AP_Mol_Mass 58 kDa
      Tag C-His
      Bio_Activity Immobilized Human TIGIT-Fc(Cat: PKSH033510) at 5μg/ml(100 μl/well) can bind Human PVR-His. The ED50 of Human PVR-His is 11.66 ug/ml .

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.

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      MSDS for ELISA ISO 9001

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