Recombinant Human CD24 Protein (Ser27-Gly59,Ser44Thr)(Fc Tag)

    • Recombinant Human CD24  Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human CD24  Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human CD24  Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033527

      Synonyms:Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A;FLJ22950;FLJ43543;MGC75043

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $92

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A;FLJ22950;FLJ43543;MGC75043
      Species Human
      Expression_host Human Cells
      Sequence Ser27-Gly59(Ser44Thr)
      Accession P25063
      Mol_Mass 29.8 kDa
      AP_Mol_Mass 40-55 kDa
      Tag C-Fc

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Signal Transducer CD24 is a heavily and variably glycosylated GPI-linked sialoprotein. Human CD24 is expressed on B lineage cells and granulocytes, on epithelial, neuronal, and muscle cells, and on a range of tumor cells. CD24 expression is regulated during lineage development and with the activation of various cell types. Antibody crosslinking of CD24 enhances the induction of apoptosis in B and T lymphocytes which contributes to negative selection and the induction of immune tolerance. CD24 on antigen presenting cells cooperates with B7 molecules in the costimulation of T cells. CD24 associates in cis with Siglec10 and with the danger-associated molecules HMGB1, HSP70, or HSP90 which are released from necrotic or damaged cells. Formation of these ternary complexes fills a protective role: the resulting Siglec10 signaling inhibits inflammatory responses that are otherwise induced by extracellular DAMPs.

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      MSDS for ELISA ISO 9001

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