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Recombinant Human CD30/TNFRSF8 Protein (Fc Tag)

  • Cat.No.:PKSH032213

  • Expression host: Human Cells

To Purchase PKSH032213

Size:
  • 10μg
  • 50μg
Price: $80
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Description

Synonyms Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30; TNFRSF8;D1S166E
Species Human
Expression_host Human Cells
Sequence Phe19-Lys379
Accession P28908
Mol_Mass 65.2 kDa
AP_Mol_Mass 90-120 kDa
Tag C-Fc

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per µg as determined by the LAL method.
Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mMNaCl, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.

Background

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.

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