Recombinant Human CD38 Protein (Fc Tag)
Price: $ 523
Price: $ 178
Size:
50μg
10μg
Quantity:
- Expression Host: HEK293 Cells
- Accession: P28907
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Product Details
Synonyms | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADP-ribosyl cyclase 1;Cyclic ADP-ribose hydrolase 1;CD38 antigen;CD38 molecule;CD38 |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Val43-Ile300 |
Accession | P28907 |
Calculated Molecular Weight | 57.0 kDa |
Observed Molecular Weight | 70-90 kDa |
Tag | C-Fc |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | CD38; also called ADP-ribosyl cyclase; is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate; the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes; osteoclasts; and in cardiac; pancreatic; liver and kidney cells. Through its production of cyclic ADP-ribose; CD38 modulates calcium-mediated signal transduction in many types of cells; including neutrophils and pancreatic beta cells. |