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Recombinant Human CD38 Protein (Fc Tag)

Cat:PKSH033778
Manual MSDS

Price: $ 523

Price: $ 178

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: P28907
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Product Details
Synonyms ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADP-ribosyl cyclase 1;Cyclic ADP-ribose hydrolase 1;CD38 antigen;CD38 molecule;CD38
Species Human
Expression Host HEK293 Cells
Sequence Val43-Ile300
Accession P28907
Calculated Molecular Weight 57.0 kDa
Observed Molecular Weight 70-90 kDa
Tag C-Fc
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background CD38; also called ADP-ribosyl cyclase; is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate; the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes; osteoclasts; and in cardiac; pancreatic; liver and kidney cells. Through its production of cyclic ADP-ribose; CD38 modulates calcium-mediated signal transduction in many types of cells; including neutrophils and pancreatic beta cells.