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Recombinant Human CD96 Protein (His Tag)(Active)

  • Cat.No.:PKSH033505

  • Expression host: Human Cells

To Purchase PKSH033505

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  • 10μg
  • 50μg
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Description

Synonyms T-cell surface protein tactile; Cell surface antigen CD96; T cell-activated increased late expression protein; CD96
Species Human
Expression_host Human Cells
Sequence Val22-Met503
Accession P40200-2
Application Functional ELISA
Mol_Mass 54.4 kDa
AP_Mol_Mass 120-130 kDa
Tag C-His
Bio_Activity Immobilized Human PVR-His(Cat: PKSH033563) at 10μg/ml(100 μl/well) can bind Biotinylated Human CD96-His. The ED50 of Human CD96-His is 27.54μg/mL.

Properties

Purity > 90% as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg as determined by the LAL method.
Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Please refer to the printed manual for detailed information.

Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), anectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells.

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