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Recombinant Human CEACAM1/CD66a Protein (His Tag)

Uniprot : P13688
  • Cat.No.:PKSH033739

  • Expression host: HEK293 Cells

To Purchase PKSH033739

Size:
  • 10μg
  • 50μg
Price: $98
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Description

Synonyms Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1;Biliary Glycoprotein 1;BGP-1;CD66a;CEACAM1;BGP;BGP1
Species Human
Expression_host HEK293 Cells
Sequence Gln35-Gly428
Accession P13688
Mol_Mass 44.3 kDa
AP_Mol_Mass 60-90 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed man
Reconstitution Please refer to the printed manual for detailed information.

Background

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.

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