Synonyms	Complement Factor H-Related Protein 2;FHR-2;DDESK59;H Factor-Like 3;H Factor-Like Protein 2;CFHR2;CFHL2;FHR2;HFL3
Species	Human
Expression_host	HEK293 Cells
Sequence	Glu19-Lys270
Accession	P36980
Mol_Mass	29.8 kDa
AP_Mol_Mass	31&35 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 200mM NaCl, 2mM EDTA, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Complement Factor H-Related Protein 2 (CFHR2) is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 is synthesized as a 270 amino acid precursor that contains an 18 amino acid signal peptide and a 252 amino acid mature chain with 4 Sushi (CCP/SCR) domains. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.

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