Recombinant Human CHI3L1/YKL40 Protein (His Tag)

    • Recombinant Human Chitinase-3-like protein 1 / CHI3L1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human Chitinase-3-like protein 1 / CHI3L1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human Chitinase-3-like protein 1 / CHI3L1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033717

      Synonyms:Chitinase-3-Like protein 1; 39 kDa Synovial Protein; Cartilage Glycoprotein 39; CGP-39; GP-39; hCGP-39; YKL-40; CHI3L1;ASRT7;DKFZp686N19119;FLJ38139;GP39;HC-gp39;HCGP-3P;YKL40;YYL-40

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      • 10μg
      • 50μg
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      Price: $98

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      Overview

      Synonyms Chitinase-3-Like protein 1; 39 kDa Synovial Protein; Cartilage Glycoprotein 39; CGP-39; GP-39; hCGP-39; YKL-40; CHI3L1;ASRT7;DKFZp686N19119;FLJ38139;GP39;HC-gp39;HCGP-3P;YKL40;YYL-40
      Species Human
      Expression_host Human Cells
      Sequence Tyr22-Thr383
      Accession P36222
      Mol_Mass 41.5 kDa
      AP_Mol_Mass 46 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.

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