Recombinant Human CRADD/RAIDD Protein
Price: $ 523
Price: $ 178
Size:
50μg
10μg
Quantity:
- Expression Host: E.coli
- Accession: P78560
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Product Details
Synonyms | Death Domain-Containing Protein CRADD;Caspase and RIP Adapter with Death Domain;RIP-Associated Protein with A Death Domain;CRADD;RAIDD |
Species | Human |
Expression Host | E.coli |
Sequence | Met1-Glu199 |
Accession | P78560 |
Calculated Molecular Weight | 23 kDa |
Observed Molecular Weight | 21 kDa |
Tag | None |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues; with particularly high expression in the adult heart; testis; liver; skeletal muscle; fetal liver; and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2; and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation. |