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Recombinant Human CSF2RA/GM-CSFR Protein (His Tag)(Active)

Uniprot : P15509
  • Cat.No.:PKSH033281

  • Expression host: HEK293 Cells

To Purchase PKSH033281

  • 10µg
  • 50µg
Price: $111


Synonyms Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha, GM-CSF-R-Alpha, GMCSFR-Alpha, GMR-Alpha, CDw116, CD116, CSF2RA, CSF2R, CSF2RY
Species Human
Expression_host HEK293 Cells
Sequence Glu23-Gly320
Accession P15509
Mol_Mass 35.5 kDa
AP_Mol_Mass 60 kDa
Tag C-6His
Bio_Activity Measured by its ability to inhibit GM-CSF-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.5-2 μg/ml.


Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual
Reconstitution Please refer to the printed manual for detailed information.


Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).

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