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Recombinant Human Cystatin C/CST3 Protein (Human Cells)

Uniprot : P01034
  • Cat.No.:PKSH032321

  • Expression host: HEK293 Cells

To Purchase PKSH032321

Size:
  • 10μg
  • 50μg
Price: $178
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Description

Synonyms Cystatin-C;Cystatin-3;Gamma-trace;Neuroendocrine basic polypeptide;Post-gamma-globulin;CST3
Species Human
Expression_host HEK293 Cells
Sequence Ser27-Ala146
Accession P01034
Mol_Mass 13.3 kDa
AP_Mol_Mass 15 kDa
Tag None

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 10mM PB, 200mM Nacl, pH6.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manu
Reconstitution Please refer to the printed manual for detailed information.

Background

Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B; H; K; L and S. As an inhibitor of cysteine proteinases; Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently; it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition); such as Alzheimer's disease.

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