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Recombinant Human cytomegalovirus (HCMV) Glycoprotein B / gB Protein

Uniprot : P13201
  • Cat.No.:PKSV030205

  • Expression host: HEK293 Cells

To Purchase PKSV030205

Size:
  • 100μg
Price: $1105
Qty:

Description

Synonyms Glycoprotein B;gB
Species CMV
Expression_host HEK293 Cells
Sequence Arg 777-Val 907
Accession AAA45920.1
Mol_Mass 92.0 kDa
AP_Mol_Mass 130-140 kDa
Tag None
Bio_Activity Not validated for activity

Properties

Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile Tris 50mM, NaCl 100mM, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium.

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