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Recombinant Human Dermatopontin/DPT Protein (Fc & His Tag)

Uniprot : Q07507
  • Cat.No.:PKSH032350

  • Expression host: HEK293 Cells

To Purchase PKSH032350

Size:
  • 10μg
  • 50μg
Price: $117
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Description

Synonyms Dermatopontin;Tyrosine-rich acidic matrix protein;TRAMP and DPT;
Species Human
Expression_host HEK293 Cells
Sequence Gln19-Val201
Accession Q07507
Mol_Mass 49.9 kDa
AP_Mol_Mass 50-60 kDa
Tag C-Fc-His
Bio_Activity Not validated for activity

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 4% Sucrose, 4% mannitol, 0.02% Tween 80, pH 7.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.

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