Synonyms	Dipeptidyl peptidase 3;Dipeptidyl aminopeptidase III;Dipeptidyl arylamidase III;Dipeptidyl peptidase III;Enkephalinase B;DPP3
Species	Human
Expression_host	E.coli
Sequence	Met 1-Ala737
Accession	Q9NY33
Mol_Mass	84.8 kDa
AP_Mol_Mass	70-90 kDa
Tag	N-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 10mM NaCl, 2mM DTT, 0.05% Tween 80, 20% Glycerol, pH 8.0.
Reconstitution	Not Applicable

Background

Dipeptidyl peptidase 3(DPP3), is a member of the S9B family in clan SC of the serine proteases. DPP3 has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH). It releases an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity and also acts on dipeptidyl 2-naphthylamides.Increased activity of this protein has a relationship with endometrial and ovarian cancers.

Citations

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