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Recombinant Human DTD1 Protein (His Tag)

Uniprot : Q8TEA8
  • Cat.No.:PKSH032363

  • Expression host: HEK293 Cells

To Purchase PKSH032363

Size:
  • 10μg
  • 50μg
Price: $223
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Description

Synonyms D-tyrosyl-tRNA(Tyr) deacylase 1;DNA-unwinding element-binding protein B;DUE-B;Histidyl-tRNA synthase-related;DTD1;C20orf88;DUEB;HARS2
Species Human
Expression_host HEK293 Cells
Sequence Met 1-Pro209
Accession Q8TEA8
Mol_Mass 24.5 kDa
AP_Mol_Mass 30 kDa
Tag C-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution Not Applicable

Background

D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.

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