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Recombinant Human DUSP3/VHR Protein (His Tag)

    • Recombinant Human DUSP3 / VHR Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human DUSP3 / VHR Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human DUSP3 / VHR Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033476

      Synonyms:Dual specificity protein phosphatase 3;DUSP3;Dual specificity protein phosphatase VHR;Vaccinia H1-related phosphatase;VHR

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $263

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      Overview

      Synonyms Dual specificity protein phosphatase 3;DUSP3;Dual specificity protein phosphatase VHR;Vaccinia H1-related phosphatase;VHR
      Species Human
      Expression_host E.coli
      Sequence Ser2-Pro185
      Accession P51452
      Mol_Mass 22.6 kDa
      AP_Mol_Mass 20 kDa
      Tag N-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Human DUSP3 belongs to the dual specificity protein phosphatase subfamily. DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSPs are major modulators of critical signalling pathways that are dysregulated in various diseases. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. DUSP3 is expressed in human tissues including breast and ovarian.DUSP3 shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Human DUSP3 specifically dephosphorylates and inactivates ERK1 and ERK2.

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      MSDS for ELISA ISO 9001

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