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Recombinant Human EIF1AX Protein (His Tag)

Uniprot : P47813
  • Cat.No.:PKSH032372

  • Expression host: E.coli

To Purchase PKSH032372

Size:
  • 10μg
  • 50μg
Price: $178
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Description

Synonyms Eukaryotic Translation Initiation Factor 1A X-Chromosomal;eIF-1A X Isoform;Eukaryotic Translation Initiation Factor 4C;eIF-4C;EIF1AX;EIF1A;EIF4C
Species Human
Expression_host E.coli
Sequence Met 1-Ile144
Accession P47813
Mol_Mass 18.6 kDa
AP_Mol_Mass 22 kDa
Tag N-His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA and has been shown to interact with IPO13. EIF1AX contains one S1-like domain and seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

Citations

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