Recombinant Human FLRT1 Protein (His Tag)

    • Recombinant Human FLRT1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human FLRT1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human FLRT1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033676

      Synonyms:Leucine-Rich Repeat Transmembrane Protein FLRT1; Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 1; FLRT1

      Size:
      • 10μg
      • 50μg
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      Price: $98

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      Overview

      Synonyms Leucine-Rich Repeat Transmembrane Protein FLRT1; Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 1; FLRT1
      Species Human
      Expression_host Human Cells
      Sequence Ile21-Pro524
      Accession Q9NZU1
      Mol_Mass 56.52 kDa
      AP_Mol_Mass 77 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Fibronectin Leucine Rich Transmembrane Protein 1 (FLRT1) is a member of the Fibronectin Leucine Rich Transmembrane protein (FLRT) family. There are three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1, FLRT2 and FLRT3, all contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell association. FLRT1 is expressed at brain compartmental boundaries. FLRT1 is a target for tyrosine phosphorylation mediated by FGFR1 and implicate a non-receptor Src family kinase (SFK).

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      MSDS for ELISA ISO 9001

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