Synonyms	Glucagon-like peptide 1 receptor;GLP-1 receptor;GLP-1-R
Species	Human
Expression_host	HEK293 Cells
Sequence	Arg24-Tyr145
Accession	P43220
Mol_Mass	41.2 kDa
AP_Mol_Mass	50-75 kDa
Tag	C-Fc

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

GLP1R Belongs to the G-protein coupled receptor 2 family that is synthesized as a 172 amino acid (aa). GLP1R is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. It may form homodimers and heterodimers with GIPR. GLP1R is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Citations

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