Synonyms	Glutamine Synthetase;GS;Glutamate Decarboxylase;Glutamate--Ammonia Ligase;GLUL;GLNS
Species	Human
Expression_host	E.coli
Sequence	Thr 2-Asn373
Accession	P15104
Mol_Mass	43.1 kDa
AP_Mol_Mass	40-50 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 50mM Imidazole, pH 8.0.
Reconstitution	Not Applicable

Background

Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of energy and that takes part in cell prolifetation, inhibition of apoptosis, and cell signaling. Glutamine Synthetase is expressed during early fetal stages, and has a role in maintaining body PH by removing ammonia from circulation. Mutations in the GLUL gene are related to congenital glutamine deficiency.

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