Recombinant Human GM-CSF/CSF2 Protein (E.coli)(Active)

    • Recombinant Human GM-CSF / CSF2 Protein-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human GM-CSF / CSF2 Protein-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human GM-CSF / CSF2 Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033662

      Synonyms:Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $144

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; CSF2; GMCSF
      Species Human
      Expression_host E.coli
      Sequence Ala18-Glu144
      Accession P04141
      Application Cell Culture
      Mol_Mass 14.6 kDa
      AP_Mol_Mass 14 kDa
      Bio_Activity Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 4-20 pg/ml.

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.

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