Recombinant Human HMGB1 Protein

    • Recombinant Human HMGB1 / HMG1 Protein-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human HMGB1 / HMG1 Protein-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human HMGB1 / HMG1 Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033654

      Synonyms:High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $129

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      Overview

      Synonyms High Mobility Group Protein B1; High Mobility Group Protein 1; HMG-1; HMGB1; HMG1
      Species Human
      Expression_host E.coli
      Sequence Gly2-Phe89
      Accession P09429
      Mol_Mass 10.5 kDa
      AP_Mol_Mass 14 kDa

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 50mMHepes,500mMNaCl,0.5mMDTT, pH7.9 .
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.

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      MSDS for ELISA ISO 9001

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