Recombinant Human ICOS/AILIM Protein (Fc Tag)

    • Recombinant Human ICOS / AILIM / CD278 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human ICOS / AILIM / CD278 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human ICOS / AILIM / CD278 Protein (C-Fc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033644

      Synonyms:Inducible T-cell costimulator;activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1;ICOS;

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $117

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      Overview

      Synonyms Inducible T-cell costimulator;activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1;ICOS;
      Species Human
      Expression_host Human Cells
      Sequence Glu21-Phe141
      Accession Q9Y6W8
      Mol_Mass 40.8 kDa
      AP_Mol_Mass 47 kDa
      Tag C-Fc

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Inducible T-cell costimulator, also known as activation-inducible lymphocyte immunomediatory molecule, CD278, AILIM, CVID1 and ICOS, belongs to the CD28 and CTLA4 cell surface receptor family.. ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked. ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin, ICOS plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Defects in ICOS are the cause of immunodeficiency common variable type 1, which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antige

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      MSDS for ELISA ISO 9001

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