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Recombinant Human IFNGR1 Protein (His Tag)

Uniprot : P15260
  • Cat.No.:PKSH033429

  • Expression host: HEK293 Cells

To Purchase PKSH033429

Size:
  • 10µg
  • 50µg
Price: $209
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Description

Synonyms CD119, IFNGR, IMD27A, IMD27B, Interferon gamma receptor 1, IFNGR1
Species Human
Expression_host HEK293 Cells
Sequence Glu18-Ser245
Accession P15260
Mol_Mass 28.7 kDa
AP_Mol_Mass 40-50 kDa
Tag C-6His
Bio_Activity Testing in progress

Properties

Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Not Applicable

Background

Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

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