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Recombinant Human IL7RA/CD127 Protein (Fc & His Tag)

Uniprot : P16871

Cat.No.:PKSH033609
Expression host: HEK293 Cells

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Description

Synonyms	CD127;CDW127;IL-7R;IL-7R-alpha;IL7RA;ILRA;Interleukin-7 receptor subunit alpha;IL7R
Species	Human
Expression_host	HEK293 Cells
Sequence	Glu21-Gly236
Accession	P16871
Mol_Mass	52.8 kDa
AP_Mol_Mass	75 kDa
Tag	C-Fc-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.

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