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Recombinant Human Interleukin-17F/IL-17F Protein

Cat:PKSH032622
Manual MSDS

Price: $ 739

Price: $ 249

Size:
100μg 20μg
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  • Expression Host: E.coli
  • Accession: Q96PD4
  • Applications: Cell culture
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Product Details
Synonyms Interleukin-17F;IL-17F;Cytokine ML-1;Interleukin-24;IL-24;IL17F;IL24
Species Human
Expression Host E.coli
Sequence Arg31-Gln163
Accession Q96PD4
Calculated Molecular Weight 15.8 kDa
Observed Molecular Weight 18 kDa
Tag C-His
Bio-activity Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED<sub>50</sub> for this effect is <20 ng/mL.
Purity > 98 % as determined by reducing SDS-PAGE.
Endotoxin < 0.1 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 20 mM sodium acetate, pH 4.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today; IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family; IL-17A through IL-17F; are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.