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Recombinant Human Interleukin-2/IL-2 Protein (C145S)(Active)

Uniprot : P60568
  • Cat.No.:PKSH033623

  • Expression host: E.coli

To Purchase PKSH033623

Size:
  • 10µg
  • 50µg
Price: $62
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Description

Synonyms Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL6
Species Human
Expression_host E.coli
Sequence Pro22-Thr153(Cys145Ser)
Accession P60568
Application Cell Culture
Mol_Mass 15.5 kDa
AP_Mol_Mass 14 kDa
Bio_Activity Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 90-270 pg/ml

Properties

Purity > 95% as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg as determined by the LAL method.
Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 10mM Acetata-Na, 5% Trehaiose, pH 4.5.
Reconstitution Please refer to the printed manual for detailed information.

Background

Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

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