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Recombinant Human Interleukin-2/IL-2 Protein (Mutant)(Active)

Uniprot : P60568
  • Cat.No.:PKSH033625

  • Expression host: HEK293 Cells

To Purchase PKSH033625

  • 10µg
  • 50µg
Price: $62


Synonyms Interleukin-2, IL-2, T-Cell Growth Factor, TCGF, Aldesleukin, IL3
Species Human
Expression_host HEK293 Cells
Sequence Ala21-Thr153(L100F;R101D;L105V;I106V;I112F)
Accession P60568
Application Cell Culture
Mol_Mass 16.5 kDa
AP_Mol_Mass 16&18 kDa
Tag C-His
Bio_Activity Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The specific activity of Recombinant Human IL-2 is ≥1×107 IU/mg.


Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.


Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.

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