Recombinant Human Interleukin-7/IL-7 Protein (Active)

    • Recombinant Human IL-7 / Interleukin-7 Protein-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human IL-7 / Interleukin-7 Protein-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human IL-7 / Interleukin-7 Protein-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033610

      Synonyms:Interleukin-7; IL-7; IL7

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $178

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Interleukin-7; IL-7; IL7
      Species Human
      Expression_host E.coli
      Sequence Asp26-His177
      Accession P13232
      Application Cell Culture
      Mol_Mass 17.5 kDa
      AP_Mol_Mass 18 kDa
      Bio_Activity Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.02-0.08ng/ml.

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mMPB, 300mMNaCl, pH8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.

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      MSDS for ELISA ISO 9001

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