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Recombinant Human IRF5 Protein (His Tag)

Cat:PKSH032603
Manual MSDS

Price: $ 523

Price: $ 178

Size:
50μg 10μg
Quantity:
  • Expression Host: E.coli
  • Accession: Q13568
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Product Details
Synonyms Interferon Regulatory Factor 5;IRF-5;IRF5
Species Human
Expression Host E.coli
Sequence Met 1-Gln498
Accession Q13568
Calculated Molecular Weight 57.1 kDa
Observed Molecular Weight 62 kDa
Tag C-His
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 30% Glycerol, 1mM DTT, pH 8.0.
Reconstitution Not Applicable
Background Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.