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Recombinant Human Ketohexokinase/KHK Protein (His Tag)

Uniprot : P50053

Cat.No.:PKSH032672
Expression host: HEK293 Cells

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Description

Synonyms	Ketohexokinase;Hepatic fructokinase;KHK
Species	Human
Expression_host	HEK293 Cells
Sequence	Met 1-Val298
Accession	AAH06233.1
Mol_Mass	33.7 kDa
AP_Mol_Mass	30 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50nM KCl, 10% Glycerol, pH 7.4.
Reconstitution	Not Applicable

Background

Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.

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