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Recombinant Human Lactotransferrin/LTF Protein (His Tag)

Uniprot : P02788

Cat.No.:PKSH032679
Expression host: HEK293 Cells

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Description

Synonyms	Lactotransferrin;Lactoferrin;Talalactoferrin;Kaliocin-1;Lactoferroxin-A;Lactoferroxin-B;Lactoferroxin-C;LTF;LF;GIG12;HEL110;HLF2
Species	Human
Expression_host	HEK293 Cells
Sequence	Gly20-Lys711
Accession	AAH15822.1
Mol_Mass	77.3 kDa
AP_Mol_Mass	90 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed man
Reconstitution	Please refer to the printed manual for detailed information.

Background

Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; and Lactoferroxin-C. Lactoferroxin A; Lactoferroxin B; and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors; while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide; fungicide) and is part of the innate defense; mainly at mucoses.

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