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Recombinant Human LAMP2/CD107b Protein (His Tag)

Uniprot : P13473
  • Cat.No.:PKSH032684

  • Expression host: HEK293 Cells

To Purchase PKSH032684

  • 10μg
  • 50μg
Price: $98


Synonyms Lysosome-Associated Membrane Glycoprotein 2;LAMP-2;Lysosome-Associated Membrane Protein 2;CD107 Antigen-Like Family Member B;CD107b;LAMP2
Species Human
Expression_host HEK293 Cells
Sequence Leu29-Ile375
Accession P13473
Application Functional ELISA
Mol_Mass 39.4 kDa
AP_Mol_Mass 60-120 kDa
Tag C-His


Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed man
Reconstitution Please refer to the printed manual for detailed information.


Lysosomal Associated Membrane Protein 2 (LAMP2) is a major component of lysosomal membranes. LAMP2 is a transmembrane glycoprotein about 110kDa. Mature human LAMP2 consists of a 347 amino acid (aa) intralumenal domain, a 24 aa transmembrane segment, and a 35 aa cytoplasmic tail . The lumenal domain is organized into two heavily N-glycosylated regions. Alternate splicing generates a human LAMP2 isoform (LAMP2B) with a substituted juxtamembrane lumenal region, cytoplasmic tail and transmenmbrane segment.LAMP2 itself can cleavage lysosomal luminal domain and degradation lysosomal. In the help of chaperone HSC73,LAMP2 mediates the lysosomal uptake in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles.

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