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Recombinant Human Leukocyte Ig-Like Receptor B1/ LILRB1/ILT2/CD85j (C-Fc)

Uniprot : D9IDM8

Cat.No.:PKSH033978
Expression host: Human Cells

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Description

Synonyms	Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1; LIR-1; Leukocyte Immunoglobulin-Like Receptor 1; CD85 Antigen-Like Family Member J; Immunoglobulin-Like Transcript 2; ILT-2; Monocyte/Macrophage Immunoglobulin-Like Receptor 7; MIR-7; CD85j; LILRB1; ILT2; LIR1; MIR7
Species	Human
Expression_host	Human Cells
Sequence	Gly24-His458
Accession	D9IDM8
Mol_Mass	74.1 kDa
AP_Mol_Mass	100-120 kDa
Tag	C-Fc

Properties

Purity	>95% as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per µg as determined by the LAL method.
Storage	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution	Please refer to the printed manual for detailed information.

Background

The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.

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